A United States army vehicle hit an improvised explosive device as it entered a firing range during a training exercise near the town of Oullam, south-west Niger republic.
The army in a statement said there were no fatalities but the soldiers are being evaluated. The soldiers were travelling in a mine-resistant vehicle when the explosion happened.
The US is supporting Niger republic in its fight against terrorists in the region.
In 2017, four US soldiers and four Nigerian soldiers were killed in an ambush near the Malian border.