The Super Eagles left their camp in Alexandria for Cairo, the capital city to begin preparations for the quarterfinal showdown against the Bafana Bafana of South Africa.
The match, which holds in Cairo tomorrow, will be another grudge game between the two countries.
The Bafana Bafana nearly prevented the Super Eagles from making it to Egypt 2019 AFCON following a shock 2-0 defeat of the Nigerians in their home ground, Uyo, in the first leg of the qualifiers in 2018.
It took extra efforts from the Super Eagles to overcome the impact of that defeat, having missed two previous editions of the AFCON in 2015 and 2017.
While the Super Eagles secured their quarterfinal ticket at the expense of Cameroun, Bafana Bafana edged out the host nation, Egypt to create one of the biggest upsets in the competition.